Our plans to add Togoto the WHO list of Malaria Free- Countries… A never-been-done-before-in-Africa malaria pilot study.

Project Background:

After meeting with Togo’s Ministries ofAgriculture, Environment, Safety and Civil Aviation, Health and SocialProtection, and representatives from the University of Lomé, and The WorldBank, Assi le Assime: The Togo Development Partnership proposed a pilot study to eliminate the vector (mosquitoes) that transmits the parasite which causesmalaria through aerial spraying of a biopesticide. Sponsored by Assi le Assime(www.assileassime.org), and written by researchers from the Togoleseministries, the protocol will be submitted to the National Bioethics Committeefor review in 2018; when approved, the first phase of the study would begin inFall 2018.

The protocol team wrote:

“…the path to (malaria) elimination is still long because the efforts beingmade face a certain number of limitations. One of the limitations is routineand lack of ambition to attempt innovative or new strategies that were testedin certain regions of the world where malaria formerly raged. Specifically, howcan we proceed toward the elimination of malaria when vector control, one ofthe control methods on the forefront for tens of years is only limited toresidual indoor spraying? How do we understand that vector control by aerialspraying, significantly tried and true in certain countries in the world hasnot yet been introduced in Africa? ThisAmerican-Togolese innovative project is positions as an alternative pilotapproach and aims to eliminate malaria in Togo…”.

Data Analysis:

We will prepare the data analysis plan,andcreate an electronic case report form for both the mosquito and the human data. We will analyse the data from 6 collection sites in 2 zones (study andcontrol zones) for both humans and mosquitoes, to correlate the decrease inmosquitoes which carry the malaria parasite with the decrease in the incidenceof malaria in humans.

Data Collection and Storage:

We will use electronic data collectionforms, input onto tablets in the field, connected to a wifi network, and storedin the cloud, where it can be reviewed, verified, and analysed remotely.


The final protocol will be submitted to theTogolese Bioethics Committee on July 31, 2018.When approved, data capture will begin in September 2018 through November2019. Aerial application data will becollected from May through November 2019.